翟红林 (教授)★

翟红林教授(Prof. H. L. Zhai)，男，博士生导师。1964年出生，1986年6月兰州大学化学系物理化学本科专业毕业获学士学位并留校工作至今。2004年12月获分析化学博士学位，2007年1月至2008年1月赴台湾长庚大学分子医学研究中心开展抗癌药物设计及癌症早期诊断的博士后研究工作。专业特长为数据建模与分析、程序设计与应用；目前主要从事复杂体系中的多组分同时定性与定量分析、实验条件优化、药物分子与蛋白质相互作用模拟、药物分子设计及计算机技术在化学等相关领域应用的教学与科研工作。已在Analyst、Analytica Chimica Acta、Food Chemistry、J. Chromatography A、Talanta、Journal of Separation Science、J. Chemical Information and Modeling、Chemometrics and Intelligent Laboratory Systems、Chemical Biology & Drug Design、Computational Biology & Chemistry等国内外刊物上发表论文六十余篇；目前主持国家自然科学基金面上项目一项。

近期发表的代表性论文：

1.      Krawtchouk image moment method for the simultaneous determination of three drugs in human plasma based on fluorescence three-dimensional spectra. Talanta, 2016, 161: 99-104.

2.      An approach to the quantitative analysis of multiple components based on liquid chromatography mass spectrometry in full scan mode. Journal of Separation Science, 2016, 39(15): 3054-3061.

3.      Insights into mechanism of Pyrido[2,3-d]pyrimidines as DYRK1A inhibitors based on molecular dynamic simulations. PROTEINS: Structure, Function, and Bioinformatics, 2016, 84(8): 1108–1123

4.      The determination of multi-components utilizing 1H NMR three-dimensional spectra combined Tchebichef moments. Chemometrics and Intelligent Laboratory Systems, 2016, 156: 128-136.

5.      Enhancing Specificity in the Janus Kinases: A Study on the Thienopyridine JAK2 Selective Mechanism Combined Molecular Dynamics Simulation. Molecular BioSystems, 2016, 12(2): 575-587.

6.      An efficient approach to the quantitative analysis of humic acid in water. Food Chemistry, 2016, 190(1): 1033-1039.

7.      Study on the active mechanism of β-secretase inhibitors by molecular simulations. European Journal of pharmaceutical sciences, 2015, 76: 138-148.

8.      The application of Tchebichef moment method on the quantitative analysis of multiple compounds based on three-dimensional HPLC fingerprint spectra. Analyst, 2015, 140(2): 630-636.

9.      A practical application of wavelet moment method on the quantitative analysis of Shuanghuanglian oral liquid based on three-dimensional fingerprint spectra. Journal of Chromatography A, 2014, 1352: 55-61.

10.  An application of wavelet moments to the similarity analysis of three-dimensional fingerprint spectra obtained by high-performance liquid chromatography coupled with diode array detector. Food Chemistry, 2014, 145: 625-631.